Computational Molecular Biology Spring 2004
Drs. Wilber Baker and Robert Styer
Problem-Based Learning (PBL Evaluation Form)
January 12-21 Problem 1 (Finding
Genes)
Promoter Info Article
Simpler but Less Detailed Promoter
Info pages
TATA
Box Sequence
Amino Acids datasheet
IUB Code Info
January 26-Feb 9 Problem 2 Restriction
Mapping (Problem 2 as Word
doc)
Restriction Enzyme
(oracle) example (equivalent
Word document)
Some Comments
on Problem 2
Feb 11-23 Problem 3 (DNA Forensics)
Feb 23-Mar 15 Problem 4 (DNA Arrays)
All You Need to Know About Graph Theory
March 11 Midterm and one Takehome question
March 17-April 7 Problem 5 (Longest superstrings) handout
April 14-19 Problem 6 (Gene translation and
prediction)
Gelfand et al paper referred to in the text is available on-line through
Falvey Library
April 19-28 Problem 7 (Modeling a genome)
Dobzhansky Sturtevant article "Inversions in the Chromosomes of Drosophila
Pseudoobscura" Genetics, Vol 23, Jan 1938, pp. 28-64, available on-line
through Falvey Library
May 3 Final Exam